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Symbol
Name
ID
Etv6
ets variant 6
MGI:109336
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgE level
Leukocytosis
Acute myeloid leukemia
Eczematoid dermatitis
Disease(s) Associated with ETV6
acute myeloid leukemia
thrombocytopenia

Mouse Phenotypes
immune system phenotype
increased spleen weight
abnormal lymphopoiesis
abnormal B cell differentiation
decreased pro-B cell number
arrested B cell differentiation
myeloid hyperplasia
decreased neutrophil cell number
abnormal B cell number
decreased B cell number
decreased pre-B cell number
decreased lymphocyte cell number
increased large unstained cell number
Availability Mouse Genotype
Etv6em1(IMPC)Rbrc/Etv6+
Etv6em3Knic/Etv6+
Etv6tm2Sho/Etv6tm2Sho
Tg(Mx1-cre)1Cgn/?  (conditional)
Etv6tm1(RUNX1)Haho/Etv6+
Tg(Gata1-cre)1Sho/0  (conditional)
*
Etv6tm1(RUNX1)Haho/Etv6+
Tg(CD2-icre)4Kio/0  (conditional)
*
Etv6tm1(RUNX1)Haho/Etv6+
Tg(Mx1-cre)1Cgn/0  (conditional)
*
Etv6tm1(RUNX1)Haho/Etv6+
Tg(VAV1-cre)1Graf/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory